{"id":1185,"date":"2023-10-17T12:39:48","date_gmt":"2023-10-17T12:39:48","guid":{"rendered":"https:\/\/oncologytweetorials-ce.com\/?p=1185"},"modified":"2023-10-18T12:28:12","modified_gmt":"2023-10-18T12:28:12","slug":"cat4","status":"publish","type":"post","link":"https:\/\/oncologytweetorials-ce.com\/cat4\/","title":{"rendered":"Determination of the risk of stroke in patients with atrial fibrillation and cancer: Current and emerging paradigms"},"content":{"rendered":"\n<blockquote class=\"twitter-tweet\"><p lang=\"en\" dir=\"ltr\">1b) With the burgeoning <a href=\"https:\/\/twitter.com\/hashtag\/AFib?src=hash&amp;ref_src=twsrc%5Etfw\">#AFib<\/a> population worldwide, effective <a href=\"https:\/\/twitter.com\/hashtag\/SPAF?src=hash&amp;ref_src=twsrc%5Etfw\">#SPAF<\/a> is hindered by <a href=\"https:\/\/twitter.com\/hashtag\/adherence?src=hash&amp;ref_src=twsrc%5Etfw\">#adherence<\/a> issues, <a href=\"https:\/\/twitter.com\/hashtag\/underprescribing?src=hash&amp;ref_src=twsrc%5Etfw\">#underprescribing<\/a>, &amp; <a href=\"https:\/\/twitter.com\/hashtag\/underdosing?src=hash&amp;ref_src=twsrc%5Etfw\">#underdosing<\/a>. Meanwhile <a href=\"https:\/\/twitter.com\/hashtag\/cancer?src=hash&amp;ref_src=twsrc%5Etfw\">#cancer<\/a>-assoc&#39;d <a href=\"https:\/\/twitter.com\/hashtag\/thrombosis?src=hash&amp;ref_src=twsrc%5Etfw\">#thrombosis<\/a> <a href=\"https:\/\/twitter.com\/hashtag\/CAT?src=hash&amp;ref_src=twsrc%5Etfw\">#CAT<\/a> remains a challenge w\/ debates over whether we are underestimating risk of <a href=\"https:\/\/twitter.com\/hashtag\/stroke?src=hash&amp;ref_src=twsrc%5Etfw\">#stroke<\/a> in <a href=\"https:\/\/twitter.com\/hashtag\/cancer?src=hash&amp;ref_src=twsrc%5Etfw\">#cancer<\/a> pts.<\/p>&mdash; @onc_ce (@onc_ce) <a href=\"https:\/\/twitter.com\/onc_ce\/status\/1714605409317658934?ref_src=twsrc%5Etfw\">October 18, 2023<\/a><\/blockquote> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n\n\n\n<blockquote class=\"twitter-tweet\"><p lang=\"en\" dir=\"ltr\">2) This program is supported by an unrestricted educational grant from Anthos Therapeutics. Statement of accreditation, faculty disclosures at <a href=\"https:\/\/t.co\/8oShcATovC\">https:\/\/t.co\/8oShcATovC<\/a>. Earn 0.5 hr\ud83c\udd93CE\/<a href=\"https:\/\/twitter.com\/hashtag\/CME?src=hash&amp;ref_src=twsrc%5Etfw\">#CME<\/a> by following this\ud83e\uddf5&amp; follow us for more expert-authored <a href=\"https:\/\/twitter.com\/hashtag\/MedEd?src=hash&amp;ref_src=twsrc%5Etfw\">#MedEd<\/a>. <a href=\"https:\/\/twitter.com\/hashtag\/oncTwitter?src=hash&amp;ref_src=twsrc%5Etfw\">#oncTwitter<\/a> <a href=\"https:\/\/twitter.com\/hashtag\/FOAMed?src=hash&amp;ref_src=twsrc%5Etfw\">#FOAMed<\/a> <a href=\"https:\/\/twitter.com\/hashtag\/oncsm?src=hash&amp;ref_src=twsrc%5Etfw\">#oncsm<\/a><\/p>&mdash; @onc_ce (@onc_ce) <a href=\"https:\/\/twitter.com\/onc_ce\/status\/1714605432184959372?ref_src=twsrc%5Etfw\">October 18, 2023<\/a><\/blockquote> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n\n\n\n<blockquote class=\"twitter-tweet\"><p lang=\"en\" dir=\"ltr\">3b) This \u2b06\ufe0frisk of <a href=\"https:\/\/twitter.com\/hashtag\/thrombus?src=hash&amp;ref_src=twsrc%5Etfw\">#thrombus<\/a> formation &amp; arterial <a href=\"https:\/\/twitter.com\/hashtag\/thromboembolism?src=hash&amp;ref_src=twsrc%5Etfw\">#thromboembolism<\/a> (<a href=\"https:\/\/twitter.com\/hashtag\/ATE?src=hash&amp;ref_src=twsrc%5Etfw\">#ATE<\/a>), which most commonly manifests as ischemic stroke. A major component of tx for <a href=\"https:\/\/twitter.com\/hashtag\/AF?src=hash&amp;ref_src=twsrc%5Etfw\">#AF<\/a> is determination of whether <a href=\"https:\/\/twitter.com\/hashtag\/thromboprophylaxis?src=hash&amp;ref_src=twsrc%5Etfw\">#thromboprophylaxis<\/a> as <a href=\"https:\/\/twitter.com\/hashtag\/SPAF?src=hash&amp;ref_src=twsrc%5Etfw\">#SPAF<\/a> is indicated for an individual pt.<\/p>&mdash; @onc_ce (@onc_ce) <a href=\"https:\/\/twitter.com\/onc_ce\/status\/1714605435892764988?ref_src=twsrc%5Etfw\">October 18, 2023<\/a><\/blockquote> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n\n\n\n<blockquote class=\"twitter-tweet\"><p lang=\"en\" dir=\"ltr\">3d) Both <a href=\"https:\/\/twitter.com\/hashtag\/CHADS2?src=hash&amp;ref_src=twsrc%5Etfw\">#CHADS2<\/a> &amp; <a href=\"https:\/\/twitter.com\/hashtag\/CHA2DS2Vasc?src=hash&amp;ref_src=twsrc%5Etfw\">#CHA2DS2Vasc<\/a> scores guide clinicians by identifying pts w\/highest risk of developing ATE. <a href=\"https:\/\/t.co\/Vw4ycYvgBs\">pic.twitter.com\/Vw4ycYvgBs<\/a><\/p>&mdash; @onc_ce (@onc_ce) <a href=\"https:\/\/twitter.com\/onc_ce\/status\/1714605438904221815?ref_src=twsrc%5Etfw\">October 18, 2023<\/a><\/blockquote> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n\n\n\n<blockquote class=\"twitter-tweet\"><p lang=\"en\" dir=\"ltr\">3f) Hu et al (\ud83d\udd13 <a href=\"https:\/\/t.co\/jWruZAcgpQ\">https:\/\/t.co\/jWruZAcgpQ<\/a>) have shown that in <a href=\"https:\/\/twitter.com\/hashtag\/cancer?src=hash&amp;ref_src=twsrc%5Etfw\">#cancer<\/a> patients with <a href=\"https:\/\/twitter.com\/hashtag\/AFib?src=hash&amp;ref_src=twsrc%5Etfw\">#AFib<\/a>, CHA2DS2Vasc significantly underestimates the risk of thromboembolism. <a href=\"https:\/\/t.co\/3dU7z3mzgQ\">pic.twitter.com\/3dU7z3mzgQ<\/a><\/p>&mdash; @onc_ce (@onc_ce) <a href=\"https:\/\/twitter.com\/onc_ce\/status\/1714605442284876086?ref_src=twsrc%5Etfw\">October 18, 2023<\/a><\/blockquote> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n\n\n\n<blockquote class=\"twitter-tweet\"><p lang=\"en\" dir=\"ltr\">4b) . . . consideration should be given to the addition of cancer to the clinical scoring system, creating a &quot;CCHA2DS2VASc Score&quot; with the first (added) C being <a href=\"https:\/\/twitter.com\/hashtag\/cancer?src=hash&amp;ref_src=twsrc%5Etfw\">#cancer<\/a> as an additional <a href=\"https:\/\/twitter.com\/hashtag\/RF?src=hash&amp;ref_src=twsrc%5Etfw\">#RF<\/a>.<\/p>&mdash; @onc_ce (@onc_ce) <a href=\"https:\/\/twitter.com\/onc_ce\/status\/1714605445984264430?ref_src=twsrc%5Etfw\">October 18, 2023<\/a><\/blockquote> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n\n\n\n<blockquote class=\"twitter-tweet\"><p lang=\"en\" dir=\"ltr\">4d) The greatest impact of a &quot;C&quot;CHA2DS2VASc score is that cancer\u2019s predictive power was comparable to age &gt; 75, \u2640\ufe0f sex, &amp; <a href=\"https:\/\/twitter.com\/hashtag\/DM?src=hash&amp;ref_src=twsrc%5Etfw\">#DM<\/a>, potentially enabling more patients at risk to start <a href=\"https:\/\/twitter.com\/hashtag\/anticoagulation?src=hash&amp;ref_src=twsrc%5Etfw\">#anticoagulation<\/a> therapy.<\/p>&mdash; @onc_ce (@onc_ce) <a href=\"https:\/\/twitter.com\/onc_ce\/status\/1714605449406820811?ref_src=twsrc%5Etfw\">October 18, 2023<\/a><\/blockquote> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n\n\n\n<blockquote class=\"twitter-tweet\"><p lang=\"en\" dir=\"ltr\">5) Finally, a prior meta-analysis measuring the predictive ability of the <a href=\"https:\/\/twitter.com\/hashtag\/CHADS2?src=hash&amp;ref_src=twsrc%5Etfw\">#CHADS2<\/a> &amp; <a href=\"https:\/\/twitter.com\/hashtag\/CHA2DS2VASC?src=hash&amp;ref_src=twsrc%5Etfw\">#CHA2DS2VASC<\/a> scores \u27a1\ufe0fthe C-statistics were 0.66 at best, suggesting the <a href=\"https:\/\/twitter.com\/hashtag\/RFs?src=hash&amp;ref_src=twsrc%5Etfw\">#RFs<\/a> included in these models do not explain all of the risk for ischemic stroke in <a href=\"https:\/\/twitter.com\/hashtag\/AF?src=hash&amp;ref_src=twsrc%5Etfw\">#AF<\/a>.<br>\ud83d\udd13<a href=\"https:\/\/t.co\/pomOq670Pj\">https:\/\/t.co\/pomOq670Pj<\/a><\/p>&mdash; @onc_ce (@onc_ce) <a href=\"https:\/\/twitter.com\/onc_ce\/status\/1714605452711911872?ref_src=twsrc%5Etfw\">October 18, 2023<\/a><\/blockquote> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n\n\n\n<blockquote class=\"twitter-tweet\"><p lang=\"en\" dir=\"ltr\">6b) These authors did point out, though, that a <a href=\"https:\/\/twitter.com\/hashtag\/CHA2DS2VASc?src=hash&amp;ref_src=twsrc%5Etfw\">#CHA2DS2VASc<\/a> score of zero is useful to identify patients with <a href=\"https:\/\/twitter.com\/hashtag\/AF?src=hash&amp;ref_src=twsrc%5Etfw\">#AF<\/a> and <a href=\"https:\/\/twitter.com\/hashtag\/cancer?src=hash&amp;ref_src=twsrc%5Etfw\">#cancer<\/a> who are at low embolic risk. <a href=\"https:\/\/t.co\/yMxcCTFPaV\">pic.twitter.com\/yMxcCTFPaV<\/a><\/p>&mdash; @onc_ce (@onc_ce) <a href=\"https:\/\/twitter.com\/onc_ce\/status\/1714605456709054826?ref_src=twsrc%5Etfw\">October 18, 2023<\/a><\/blockquote> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n\n\n\n<blockquote class=\"twitter-tweet\"><p lang=\"en\" dir=\"ltr\">7b) . . . is assoc&#39;d with an \u2b06\ufe0f incidence of <a href=\"https:\/\/twitter.com\/hashtag\/stroke?src=hash&amp;ref_src=twsrc%5Etfw\">#stroke<\/a>, <a href=\"https:\/\/twitter.com\/hashtag\/TIA?src=hash&amp;ref_src=twsrc%5Etfw\">#TIA<\/a>, or systemic <a href=\"https:\/\/twitter.com\/hashtag\/ATE?src=hash&amp;ref_src=twsrc%5Etfw\">#ATE<\/a> compared with matched controls without <a href=\"https:\/\/twitter.com\/hashtag\/cancer?src=hash&amp;ref_src=twsrc%5Etfw\">#cancer<\/a>. <a href=\"https:\/\/t.co\/HxZyFTXKWV\">pic.twitter.com\/HxZyFTXKWV<\/a><\/p>&mdash; @onc_ce (@onc_ce) <a href=\"https:\/\/twitter.com\/onc_ce\/status\/1714605460538499507?ref_src=twsrc%5Etfw\">October 18, 2023<\/a><\/blockquote> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n\n\n\n<blockquote class=\"twitter-tweet\"><p lang=\"en\" dir=\"ltr\">9) So, where are we? Risk and incidence of <a href=\"https:\/\/twitter.com\/hashtag\/cancer?src=hash&amp;ref_src=twsrc%5Etfw\">#cancer<\/a>, cancer-associated thrombosis <a href=\"https:\/\/twitter.com\/hashtag\/CAT?src=hash&amp;ref_src=twsrc%5Etfw\">#CAT<\/a>, and <a href=\"https:\/\/twitter.com\/hashtag\/AFib?src=hash&amp;ref_src=twsrc%5Etfw\">#AFib<\/a> intersect and interact. Cancer pts have a higher bleeding risk when treated with <a href=\"https:\/\/twitter.com\/hashtag\/anticoagulants?src=hash&amp;ref_src=twsrc%5Etfw\">#anticoagulants<\/a>&#8211;whether for <a href=\"https:\/\/twitter.com\/hashtag\/SPAF?src=hash&amp;ref_src=twsrc%5Etfw\">#SPAF<\/a> or for <a href=\"https:\/\/twitter.com\/hashtag\/CAT?src=hash&amp;ref_src=twsrc%5Etfw\">#CAT<\/a>. Tough spot!<\/p>&mdash; @onc_ce (@onc_ce) <a href=\"https:\/\/twitter.com\/onc_ce\/status\/1714605464745398660?ref_src=twsrc%5Etfw\">October 18, 2023<\/a><\/blockquote> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n\n\n\n<blockquote class=\"twitter-tweet\"><p lang=\"en\" dir=\"ltr\">11a) <a href=\"https:\/\/twitter.com\/hashtag\/AF?src=hash&amp;ref_src=twsrc%5Etfw\">#AF<\/a> often pre-exists in pts with newly dx&#39;d cancer, &amp; occurs w\/ \u2b06\ufe0f frequency shortly after <a href=\"https:\/\/twitter.com\/hashtag\/cancer?src=hash&amp;ref_src=twsrc%5Etfw\">#cancer<\/a> dx. Patients with active cancer and AF have a particularly high risk of thromboembolic complications, as both conditions carry a risk of <a href=\"https:\/\/twitter.com\/hashtag\/thrombosis?src=hash&amp;ref_src=twsrc%5Etfw\">#thrombosis<\/a>.<\/p>&mdash; @onc_ce (@onc_ce) <a href=\"https:\/\/twitter.com\/onc_ce\/status\/1714605467903594652?ref_src=twsrc%5Etfw\">October 18, 2023<\/a><\/blockquote> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n\n\n\n<blockquote class=\"twitter-tweet\"><p lang=\"en\" dir=\"ltr\">11c) (cont)<br>\ud83d\udcc8anticancer regimens (e.g., platinum compounds, anti-angiogenic tx, immune modulators)<br>\ud83d\udcc8comorbidities (e.g., obesity, kidney disease)<br>\ud83d\udcc8concurrent therapies (e.g., surgery, central catheters)<a href=\"https:\/\/t.co\/Yz3iSiIFMJ\">https:\/\/t.co\/Yz3iSiIFMJ<\/a><\/p>&mdash; @onc_ce (@onc_ce) <a href=\"https:\/\/twitter.com\/onc_ce\/status\/1714606966675276208?ref_src=twsrc%5Etfw\">October 18, 2023<\/a><\/blockquote> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n\n\n\n<blockquote class=\"twitter-tweet\"><p lang=\"en\" dir=\"ltr\">13a) So as seen in recent <a href=\"https:\/\/twitter.com\/hashtag\/tweetorials?src=hash&amp;ref_src=twsrc%5Etfw\">#tweetorials<\/a> here (still available for \ud83c\udd93CE\/<a href=\"https:\/\/twitter.com\/hashtag\/CME?src=hash&amp;ref_src=twsrc%5Etfw\">#CME<\/a> credit), e.g.:<br>\ud83d\udd17 <a href=\"https:\/\/t.co\/UlxbZuIgvi\">https:\/\/t.co\/UlxbZuIgvi<\/a><br>\ud83d\udd17<a href=\"https:\/\/t.co\/OQZyzk57I2\">https:\/\/t.co\/OQZyzk57I2<\/a><br>\ud83d\udd17 <a href=\"https:\/\/t.co\/UiRKoc7tVo\">https:\/\/t.co\/UiRKoc7tVo<\/a>), there may be an emerging option for safer &amp; more predictable <a href=\"https:\/\/twitter.com\/hashtag\/anticoagulation?src=hash&amp;ref_src=twsrc%5Etfw\">#anticoagulation<\/a> for both <a href=\"https:\/\/twitter.com\/hashtag\/SPAF?src=hash&amp;ref_src=twsrc%5Etfw\">#SPAF<\/a> &amp; <a href=\"https:\/\/twitter.com\/hashtag\/CAT?src=hash&amp;ref_src=twsrc%5Etfw\">#CAT<\/a>.<\/p>&mdash; @onc_ce (@onc_ce) <a href=\"https:\/\/twitter.com\/onc_ce\/status\/1714606969988821129?ref_src=twsrc%5Etfw\">October 18, 2023<\/a><\/blockquote> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n\n\n\n<blockquote class=\"twitter-tweet\"><p lang=\"en\" dir=\"ltr\">13c) Multiple <a href=\"https:\/\/twitter.com\/hashtag\/FXI?src=hash&amp;ref_src=twsrc%5Etfw\">#FXI<\/a> \/ <a href=\"https:\/\/twitter.com\/hashtag\/FXIa?src=hash&amp;ref_src=twsrc%5Etfw\">#FXIa<\/a>-targeted agents with different <a href=\"https:\/\/twitter.com\/hashtag\/MOAs?src=hash&amp;ref_src=twsrc%5Etfw\">#MOAs<\/a> are being investigated, none yet approved. Premise is that highly effective <a href=\"https:\/\/twitter.com\/hashtag\/antithrombotic?src=hash&amp;ref_src=twsrc%5Etfw\">#antithrombotic<\/a> therapy can be delivered w\/o compromising <a href=\"https:\/\/twitter.com\/hashtag\/hemostasis?src=hash&amp;ref_src=twsrc%5Etfw\">#hemostasis<\/a>.<\/p>&mdash; @onc_ce (@onc_ce) <a href=\"https:\/\/twitter.com\/onc_ce\/status\/1714606973256171731?ref_src=twsrc%5Etfw\">October 18, 2023<\/a><\/blockquote> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n\n\n\n<blockquote class=\"twitter-tweet\"><p lang=\"en\" dir=\"ltr\">15) <a href=\"https:\/\/twitter.com\/hashtag\/Abelacimabis?src=hash&amp;ref_src=twsrc%5Etfw\">#Abelacimabis<\/a> the only <a href=\"https:\/\/twitter.com\/hashtag\/FXI?src=hash&amp;ref_src=twsrc%5Etfw\">#FXI<\/a> inhibitor currently being investigated both for the management of <a href=\"https:\/\/twitter.com\/hashtag\/CAT?src=hash&amp;ref_src=twsrc%5Etfw\">#CAT<\/a> and for <a href=\"https:\/\/twitter.com\/hashtag\/SPAF?src=hash&amp;ref_src=twsrc%5Etfw\">#SPAF<\/a>, and is only one that dually inhibits FXI and FXIa. Phase 2 data in both indications appear promising.<\/p>&mdash; @onc_ce (@onc_ce) <a href=\"https:\/\/twitter.com\/onc_ce\/status\/1714606976041103398?ref_src=twsrc%5Etfw\">October 18, 2023<\/a><\/blockquote> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n\n\n\n<blockquote class=\"twitter-tweet\"><p lang=\"en\" dir=\"ltr\">17) In fact such management issues as <a href=\"https:\/\/twitter.com\/hashtag\/CAT?src=hash&amp;ref_src=twsrc%5Etfw\">#CAT<\/a> + <a href=\"https:\/\/twitter.com\/hashtag\/SPAF?src=hash&amp;ref_src=twsrc%5Etfw\">#SPAF<\/a> and managing the <a href=\"https:\/\/twitter.com\/hashtag\/cardiotoxic?src=hash&amp;ref_src=twsrc%5Etfw\">#cardiotoxic<\/a> effects of some <a href=\"https:\/\/twitter.com\/hashtag\/chemotx?src=hash&amp;ref_src=twsrc%5Etfw\">#chemotx<\/a> agents are at the heart of the new specialty of <a href=\"https:\/\/twitter.com\/hashtag\/cardio_oncology?src=hash&amp;ref_src=twsrc%5Etfw\">#cardio_oncology<\/a>!<br>\ud83d\udd13<a href=\"https:\/\/t.co\/jBUYFxisct\">https:\/\/t.co\/jBUYFxisct<\/a><\/p>&mdash; @onc_ce (@onc_ce) <a href=\"https:\/\/twitter.com\/onc_ce\/status\/1714606978930991154?ref_src=twsrc%5Etfw\">October 18, 2023<\/a><\/blockquote> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n\n\n\n<blockquote class=\"twitter-tweet\"><p lang=\"en\" dir=\"ltr\">18b) It&#39;s b. Cancer, which is itself <a href=\"https:\/\/twitter.com\/hashtag\/prothrombotic?src=hash&amp;ref_src=twsrc%5Etfw\">#prothrombotic<\/a> &amp; therefore often \u27a1\ufe0f <a href=\"https:\/\/twitter.com\/hashtag\/CAT?src=hash&amp;ref_src=twsrc%5Etfw\">#CAT<\/a>, is not at all uncommon in pts with <a href=\"https:\/\/twitter.com\/hashtag\/AF?src=hash&amp;ref_src=twsrc%5Etfw\">#AF<\/a>, nor is it uncommon for patients recently dx&#39;d w\/cancer to develop AF. Anticoagulation in pts w\/cancer is &gt; likely to be complicated by \ud83e\ude78than in pts w\/o cancer.<\/p>&mdash; @onc_ce (@onc_ce) <a href=\"https:\/\/twitter.com\/onc_ce\/status\/1714606983100133397?ref_src=twsrc%5Etfw\">October 18, 2023<\/a><\/blockquote> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n\n\n\n<blockquote class=\"twitter-tweet\"><p lang=\"en\" dir=\"ltr\">19b) It&#39;s d. Neither stroke nor bleeding prediction models in AF account adequately for cancer. The \u2b06\ufe0frisk of \ud83e\ude78in anticoagulated cancer pts is a problem, as are <a href=\"https:\/\/twitter.com\/hashtag\/DDIs?src=hash&amp;ref_src=twsrc%5Etfw\">#DDIs<\/a> between both <a href=\"https:\/\/twitter.com\/hashtag\/VKAs?src=hash&amp;ref_src=twsrc%5Etfw\">#VKAs<\/a> &amp; <a href=\"https:\/\/twitter.com\/hashtag\/DOACs?src=hash&amp;ref_src=twsrc%5Etfw\">#DOACs<\/a> w\/ <a href=\"https:\/\/twitter.com\/hashtag\/chemotx?src=hash&amp;ref_src=twsrc%5Etfw\">#chemotx<\/a>. Current <a href=\"https:\/\/twitter.com\/hashtag\/anticoagulants?src=hash&amp;ref_src=twsrc%5Etfw\">#anticoagulants<\/a> are \ud83d\udeab cardiotoxic, tho some chemotx is. <a href=\"https:\/\/t.co\/w42UZblyOV\">pic.twitter.com\/w42UZblyOV<\/a><\/p>&mdash; @onc_ce (@onc_ce) <a href=\"https:\/\/twitter.com\/onc_ce\/status\/1714606998916845790?ref_src=twsrc%5Etfw\">October 18, 2023<\/a><\/blockquote> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n\n\n\n<blockquote class=\"twitter-tweet\"><p lang=\"en\" dir=\"ltr\">20) And that&#39;s it! You just earned 0.5h \ud83c\udd93CE\/<a href=\"https:\/\/twitter.com\/hashtag\/CME?src=hash&amp;ref_src=twsrc%5Etfw\">#CME<\/a> and you can claim your certificate NOW at <a href=\"https:\/\/t.co\/6AlPPXS71L\">https:\/\/t.co\/6AlPPXS71L<\/a>. Click there, and then click upper right on that FOLLOW button for more expert-led <a href=\"https:\/\/twitter.com\/hashtag\/MedEd?src=hash&amp;ref_src=twsrc%5Etfw\">#MedEd<\/a>! <a href=\"https:\/\/twitter.com\/DrRohitMoudgil?ref_src=twsrc%5Etfw\">@DrRohitMoudgil<\/a> and <a href=\"https:\/\/twitter.com\/onc_ce?ref_src=twsrc%5Etfw\">@onc_ce<\/a> THANK YOU for joining us!<\/p>&mdash; @onc_ce (@onc_ce) <a href=\"https:\/\/twitter.com\/onc_ce\/status\/1714607001026560244?ref_src=twsrc%5Etfw\">October 18, 2023<\/a><\/blockquote> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n\n\n\n<iframe\n      id=\"JotFormIFrame-232893599696179\"\n      title=\"cat4 | Oncology CE 2023new\"\n      onload=\"window.parent.scrollTo(0,0)\"\n      allowtransparency=\"true\"\n      allowfullscreen=\"true\"\n      allow=\"geolocation; microphone; camera\"\n      src=\"https:\/\/form.jotform.com\/232893599696179\"\n      frameborder=\"0\"\n      style=\"min-width:100%;max-width:100%;height:1539px;border:none;\"\n      scrolling=\"no\"\n    >\n    <\/iframe>\n    <script type=\"text\/javascript\">\n    var ifr = document.getElementById(\"JotFormIFrame-232893599696179\");\n    if (ifr) {\n      var src = ifr.src;\n      var iframeParams = [];\n      if (window.location.href && window.location.href.indexOf(\"?\") > -1) {\n        iframeParams = iframeParams.concat(window.location.href.substr(window.location.href.indexOf(\"?\") + 1).split('&'));\n      }\n      if (src && src.indexOf(\"?\") > -1) {\n        iframeParams = iframeParams.concat(src.substr(src.indexOf(\"?\") + 1).split(\"&\"));\n        src = src.substr(0, src.indexOf(\"?\"))\n      }\n      iframeParams.push(\"isIframeEmbed=1\");\n      ifr.src = src + \"?\" + iframeParams.join('&');\n    }\n    window.handleIFrameMessage = function(e) {\n      if (typeof e.data === 'object') { return; }\n      var args = e.data.split(\":\");\n      if (args.length > 2) { iframe = document.getElementById(\"JotFormIFrame-\" + args[(args.length - 1)]); } else { iframe = document.getElementById(\"JotFormIFrame\"); }\n      if (!iframe) { return; }\n      switch (args[0]) {\n        case \"scrollIntoView\":\n          iframe.scrollIntoView();\n          break;\n        case \"setHeight\":\n          iframe.style.height = args[1] + \"px\";\n          if (!isNaN(args[1]) && parseInt(iframe.style.minHeight) > parseInt(args[1])) {\n            iframe.style.minHeight = args[1] + \"px\";\n          }\n          break;\n        case \"collapseErrorPage\":\n          if (iframe.clientHeight > window.innerHeight) {\n            iframe.style.height = window.innerHeight + \"px\";\n          }\n          break;\n        case \"reloadPage\":\n          window.location.reload();\n          break;\n        case \"loadScript\":\n          if( !window.isPermitted(e.origin, ['jotform.com', 'jotform.pro']) ) { break; }\n          var src = args[1];\n          if (args.length > 3) {\n              src = args[1] + ':' + args[2];\n          }\n          var script = document.createElement('script');\n          script.src = src;\n          script.type = 'text\/javascript';\n          document.body.appendChild(script);\n          break;\n        case \"exitFullscreen\":\n          if      (window.document.exitFullscreen)        window.document.exitFullscreen();\n          else if (window.document.mozCancelFullScreen)   window.document.mozCancelFullScreen();\n          else if (window.document.mozCancelFullscreen)   window.document.mozCancelFullScreen();\n          else if (window.document.webkitExitFullscreen)  window.document.webkitExitFullscreen();\n          else if (window.document.msExitFullscreen)      window.document.msExitFullscreen();\n          break;\n      }\n      var isJotForm = (e.origin.indexOf(\"jotform\") > -1) ? 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Meanwhile #cancer-assoc&#39;d #thrombosis #CAT remains a challenge w\/ debates over whether we are underestimating risk of #stroke in #cancer pts. &mdash; @onc_ce (@onc_ce) October 18, 2023 2) This program is supported by an unrestricted educational grant from Anthos [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"off","_et_pb_old_content":"","_et_gb_content_width":"","_mi_skip_tracking":false,"footnotes":""},"categories":[35],"tags":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/oncologytweetorials-ce.com\/wp-json\/wp\/v2\/posts\/1185"}],"collection":[{"href":"https:\/\/oncologytweetorials-ce.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/oncologytweetorials-ce.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/oncologytweetorials-ce.com\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/oncologytweetorials-ce.com\/wp-json\/wp\/v2\/comments?post=1185"}],"version-history":[{"count":2,"href":"https:\/\/oncologytweetorials-ce.com\/wp-json\/wp\/v2\/posts\/1185\/revisions"}],"predecessor-version":[{"id":1188,"href":"https:\/\/oncologytweetorials-ce.com\/wp-json\/wp\/v2\/posts\/1185\/revisions\/1188"}],"wp:attachment":[{"href":"https:\/\/oncologytweetorials-ce.com\/wp-json\/wp\/v2\/media?parent=1185"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/oncologytweetorials-ce.com\/wp-json\/wp\/v2\/categories?post=1185"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/oncologytweetorials-ce.com\/wp-json\/wp\/v2\/tags?post=1185"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}